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The National Invasive Species Information Center (NISIC)was established in 2005 at USDA's National Agricultural Library (NAL) to meet the information needs of users including the National Invasive Species CouncilExecutive Order 13112 established the Council in 1999.

NISIC manages the invasivespeciesinfo.gov Web site. This Web site serves as a reference gateway to information, organizations, and services about invasive species.

NISIC grew out of NAL's leadership in the development of the Invasivespecies.gov Web site for the Council. In June 2000, Invasivespecies.gov was launched as a joint collaboration between NAL, the U.S. Geological Survey, National Biological Information Infrastructure (NBII), and the Council. The site began with less than 200 external resources. By June 2005, the Web site had more than 12,000 unique resources. A major redesign was needed to enhance access to this growing wealth of resources.